Chemistry

Chemistry - Undergraduate Courses

CH 103 Introduction to General Chemistry (back to previous page)
Introductory course for students without a high school chemistry background. Fundamentals of chemistry including topics such as elements, compounds, nomenclature, and practical applications. Intended primarily for nonscience and nonengineering majors. CH 104 is taken concurrently with CH 103. 3 credit hours.

CH 104 Introduction to General Chemistry Laboratory (back to previous page)
To be taken with CH 103. Experiments include systems of measurement, the measurement of physical properties, determination of percentage of composition, chemical formulas, and chemical reactions. 1 credit hour.

CH 105 Introduction to General and Organic Chemistry with Laboratory (back to previous page)
Fundamentals of general and organic chemistry: atomic structure and properties of compounds, stoichiometry and reactions, energy relationships, states of matter, solutions, hydrocarbons, and classes of organic compounds. 4 credit hours.

CH 115 General Chemistry I (back to previous page)
Prerequisite: High school algebra or M 109, CH 103, CH 105 or one unit of high school chemistry or written qualifying exam. Brief review of fundamentals including stoichiometry, atomic structure, and chemical bonding. Other topics include thermochemistry, gas laws, properties of solution, and inorganic coordination compounds. Intended primarily for science/engineering majors. CH 117 is taken concurrently with CH 115. 3 credit hours.

CH 116 General Chemistry II (back to previous page)
Prerequisites: CH 115 , CH 117 or the equivalent. Topics include nuclear chemistry; rates of chemical reactions; chemical equilibria including pH, acid-base, common ion effect, buffers, and solubility products; thermodynamics; an introduction to organic and biochemistry. Problems in each area include environmental applications. CH 118 is taken concurrently with CH 116 . 3 credit hours.

CH 117 General Chemistry I Laboratory (back to previous page)
To be taken with CH 115. Experiments include percent composition, stoichiometry, heats of reaction, gas laws, molecular model building and colligative properties of solutions. 1 credit hour.

CH 118 General Chemistry II Laboratory (back to previous page)
To be taken with CH 116. Experiments include quantitative measurements of chemical reaction rates, equilibrium constants, the common ion effect, pH, buffers, electrochemical cells, and simple organic synthesis. 1 credit hour.

CH 201-202 Organic Chemistry I and II (back to previous page)
Prerequisites: CH 116, CH 118. Common reactions of aliphatic and aromatic chemistry with emphasis on functional groups and reaction mechanisms. CH 203-204 are taken concurrently with CH 201-202. 3 credit hours each term.

CH 203-204 Organic Chemistry I and II Laboratory (back to previous page)
To be taken with CH 201-202. Some of the techniques, reactions, and syntheses commonly employed in the organic chemistry laboratory are covered on microscale level including qualitative organic analysis and FTIR analysis. 1 credit hour each term.

CH 211 Quantitative Analysis with Laboratory (back to previous page)
Prerequisites: CH 116, CH 118. Theory and applications of acid-base, solubility, complex-formation, and oxidation-reduction equilibria to quantitative chemical analysis; introduction to statistics and evaluation of results. Laboratory analysis of samples by gravimetric and volumetric methods. 4 credit hours.

CH 221 Instrumental Methods of Analysis with Laboratory (back to previous page)
Prerequisites: CH 201, CH 203, CH 211, or permission of instructor. Theory and applications of various instrumental methods with emphasis on ultraviolet, visible, atomic absorption, fluorescence, infrared and nuclear magnetic resonance spectroscopy; mass spectrometry; gas and liquid chromatography; and potentiometry. Laboratory analysis of samples by methods discussed in the lecture. 4 credit hours.

CH 321-322 Plastics and Polymer Chemistry I and II (back to previous page)
Prerequisites: CH 116, CH 118, CH 202, CH 204 . All phases of the plastics and polymers field, including the chemistry involved, methods of production, physical properties, and the uses of specific polymers. 3 credit hours each term.

CH 331-332 Physical Chemistry I and II (back to previous page)
Prerequisites: CH 116, PH 205, M 203 (may be taken concurrently). Kinetic theory of gases, thermodynamics, phase equilibria, transport and surface phenomena, kinetics, quantum mechanics, atomic and molecular spectroscopy. CH 333-334 taken concurrently with CH 331-332. 3 credit hours each term.

CH 333-334 Physical Chemistry I and II Laboratory (back to previous page)
To be taken with CH 331-332. Laboratory training in vacuum-line techniques and real-time collection of temperature, pressure and spectrophotometric data by microcomputer. Experiments include diffusion, velocity and heat capacities of gases; calorimetry; phase diagrams of mixtures; electro-chemical properties, kinetics of fast reactions, enzyme and oscillating reactions; rotational-vibrational spectroscopy. 1 credit hour each term.

CH 341 Synthetic Methods in Chemistry (back to previous page)
Prerequisites: CH 202, CH 204, CH 221. A one-semester laboratory course covering the synthesis and characterization of inorganic and organic compounds. Performance of a variety of reactions and chemical manipulations with a focus on advanced laboratory techniques: handling air-sensitive materials, use of cryogenic conditions, separation and purification, isolation of natural products, experimental design, and safety procedures. A selection of methods for transition metal, main-group element, and aromatic and aliphatic organic syntheses. Characterization of compounds by UV, IR, NMR, mass spectrometry, and other instrumental methods. Eight hours of laboratory per week. 4 credit hours.

CH 411 Chemical Literature (back to previous page)
Prerequisites: CH 202, CH 204, CH 332. Acquaints the student with the chemical literature and its use. Assignments include library searches and online STN searching. 1 credit hour.

CH 412 Seminar (back to previous page)
Prerequisite: CH 411. The student researches a specific current topic in chemical research or applied chemistry and presents a formal seminar to the faculty and students. 1 credit hour.

CH 451 Thesis with Laboratory (back to previous page)
Prerequisites: CH 202, CH 204, CH 211, CH 221, CH 332. An original investigation in the laboratory and/or library under the guidance of a member of the department. A final thesis report is submitted. 2 credit hours.

CH 452-455 Special Topics in Chemistry (back to previous page)
Prerequisite: Consent of instructor. In-depth study of topics chosen from areas of particular and current interest to chemistry and chemical engineering students. 1-4 credit hours.

CH 471 Industrial Chemistry (back to previous page)
Prerequisites: CH 202, CH 211, CH 221, CH 332. A course to bridge the gap from the academic to the industrial world. Topics include material accounting, energy accounting, chemical transport, reactor design, process development and control. 3 credit hours.

CH 501 Advanced Organic Chemistry (back to previous page)
Prerequisites: CH 202, CH 204. This course focuses on four topics: mechanisms of organic chemistry reactions, fundamentals of synthesis of complex molecules, organic chemistry of biologically important molecules, and an introduction to medical chemistry. An underlying theme throughout this course is the relationship between chemical structure and the function and reactivity of organic compounds. 3 credit hours.

CH 521 Advanced Inorganic Chemistry (back to previous page)
Prerequisite: CH 331. Corequisite: CH 332. Review of atomic structure and introduction to group theory and symmetry. The chemistry of transition metal complexes and organometallic compounds with emphasis on bonding and structure, physical and chemical properties, and reaction mechanisms including catalysis and photochemistry. Bioinorganic chemistry and ionic solids will be covered as time permits. 3 credit hours.

CH 599 Independent Study (back to previous page)
Prerequisite: consent of instructor. Opportunity for the student under the direction of a faculty member to explore an area of interest. This course may be used to do preliminary work on the topic studied for Thesis with Laboratory (CH 451). 1-4 credit hours.

Chemistry - Graduate Courses

CH 600 Introduction to Environmental Chemistry (back to previous page)
Prerequisite: One year of undergraduate general chemistry. Designed as a prerequisite for CH 601 for students who have one year of undergraduate general chemistry, but who lack organic chemistry. Review of general and introduction to organic chemistry, with examples taken from topics of environmental concern including discussion of pollutants, toxicology, and some environmental analytic methods.

CH 601 Environmental Chemistry (back to previous page)
Prerequisite: One year of undergraduate general chemistry, plus one semester of organic chemistry or CH 600. Areas of consideration: the sources, reactions, transport, effects and fates of chemical species in the water, soil, and air environments, as well as the influence of human activities on these processes.

CH 602 Environmental Chemical Analysis (back to previous page)
Prerequisite: CH 601 or equivalent. Theory and laboratory training in the applications of instrumental methods in the analysis of environmental samples. Topics include sampling techniques; chromatography; ultraviolet-visible, infrared and atomic absorption spectroscopy; mass spectrometry; nuclear magnetic resonance spectrometry; biochemical methods; and use of radioisotopes.

CH 605 Organic Reaction Mechanisms (back to previous page)
Prerequisite: One year of undergraduate organic chemistry. This course deals with the structure and mechanisms of organic reactions, including stereochemistry and conformational analysis, acid-base catalysis, substitution, addition, and elimination reactions, as well as concerted reactions.

CH 606 Modern Organic Synthetic Methods (back to previous page)
Prerequisite: CH 605 or equivalent, or consent of instructor. A survey and discussion of methods. Topics covered include synthetic strategies, including computer-generated strategies, asymmetric syntheses, oxidation, reduction, stereocontrol and ring formation, protecting groups, nucleophilic and electrophilic species that form carbon-carbon bonds, and some complex molecules.

CH 611 Special Topics in Advanced Organic Chemistry (back to previous page)
Advanced course dealing with topics such as stereochemistry, photochemistry, natural products, and mechanisms of organic reactions.

CH 612 Molecular Structure Determination (back to previous page)
Prerequisites: Evidence of mastery of the concepts of organic chemistry and of proficiency in the basic spectroscopies. Equivalent UNH prerequisite courses are CH 202 Organic Chemistry and CH 221 Instrumental Methods of Analysis. This course focuses on the use of NMR methods and mass spectral data to elucidate structures of small to medium-size organic molecules, with an emphasis on pharmacologically active compounds and synthetic intermediates. Extensive interpretation of NMR data obtained for routine active nuclei in single and multidimensional experiments. Methods will include 1H mapping, COSY, NOE, 13C DEPT series, and other modern experiments. Utilization of low- and high-resolution mass spectral data will accompany explanations of the processes for the selection of a method of acquisition to be used to obtain structure information. Discussion of various sample introduction methods: LC, GC, DIP, maldi, and ionization techniques. The course also includes a review of the supporting spectroscopies and x-ray crystallography to culminate in developing an understanding of chemical structure determination as relevant to molecular structure identification and mixture evaluation.

CH 621 Chemical Forensic Analysis with Laboratory (back to previous page)
Advanced techniques and new developments in the identification of various materials such as pigments, dyestuffs, food additives, pharmaceutical preparations, polymers, synthetic fibers, and inorganic material products. 4 credits.

CH 625 Chemistry of Fires and Explosions (back to previous page)
An examination of the basic organic chemistry and combustion and explosive properties of flammable materials. The chemical principles underlying fires and explosions. Chemical properties of various synthetic materials and the products of their combustion. Fire-retardant materials and chemicals used in fire extinguishment. (See also FS 625).

CH 631 Advances in Analytic Chemistry (back to previous page)
Provides background on the recent advances made in instrumentation and current analytic techniques.

CH 640 Chemical Separations (back to previous page)
Prerequisites: Evidence of mastery of the concepts of chemistry as demonstrated with a B.S. degree in chemistry or biology. Students should have courses equivalent to UNH courses CH 202 Organic Chemistry and CH 221 Instrumental Methods of Analysis. Biological systems contain many thousands of different organic compounds that are present at very low concentrations. This course deals with current methods of separating, detecting, and quantifying pharmaceuticals and associated metabolites and other "small molecule" organic agents present in complex animal and agricultural samples. Clean-up methods include liquid and solid phase extractions, gel filtration, size-exclusion, ion-exchange, and affinity chromatography. Analytical methods emphasize HPLC, GC with MS and fluorescence detection, and detection-oriented derivatization. Comparison and evaluation of different techniques are presented with practical examples.

CH 650 Medicinal Chemistry I (back to previous page)
Prerequisite: One year of undergraduate organic chemistry. Recommended: an advanced undergraduate organic chemistry course. Medicinal chemistry is the investigation, discovery, and development of therapeutic agents. A key concept is the understanding of the relationship between chemical structure and drug activity. This course is interdisciplinary in its approach, with the goals of understanding drug action and designing new drugs. Medicinal chemistry incorporates knowledge of a wide scope of disciplines such as chemistry, biology, and pharmacology. This course emphasizes the fundamental principles of medicinal chemistry and surveys major classes of drugs.

CH 655 Pharmacology (back to previous page)
Prerequisites: One year of undergraduate organic chemistry and one term of biochemistry. Recommended: an advanced undergraduate organic chemistry course, at least one graduate course in biochemistry (MB 601 -MB 603), and a graduate course in cell biology (MB 607). Pharmacology is the study of therapeutics: agents administered to achieve a beneficial therapeutic effect on some disease process. This survey course will cover a general overview of pharmacology including principles of pharmacodynamics (mechanism of action of drugs) and pharmacokinetics (the role of drug absorption, distribution, metabolism, and excretion in drug action). The general concepts will be applied to case studies of specific drugs taken from the main classes of therapeutic agents.

CH 665 Combinatorial Chemistry (back to previous page)
Prerequisites: CH 650 and CH 606. Students are expected to have a strong undergraduate background in organic chemistry. Combinatorial chemistry is a relatively new approach for producing large collections of compounds for analysis. This course will cover the fundamental techniques and ideas for generating diverse libraries of compounds. Students will learn and utilize several computer packages to design, analyze, and evaluate combinatorial libraries. Examples will be drawn principally from drug design since combinatorial chemistry has had a major impact on the development of new pharmacological agents. Students anticipating careers in pharmaceutical or biotechnology industries will find this course of value.

CH 670 Selected Topics (back to previous page)
A study of selected issues of particular interest to the students and instructor. May be taken more than once.

CH 680 Graduate Seminar I (back to previous page)
Prerequisite: Permission of the instructor. Weekly discussions of current topics in medicinal chemistry and presentations of student and faculty research projects. 1 credit.

CH 681 Graduate Seminar II (back to previous page)
Prerequisite: CH 680, E 659, and permission of the instructor. Weekly discussions and seminars on current topics in medicinal chemistry will be presented by students and faculty. Students will make a formal presentation of their research. 1 credit.

CH 695 Independent Study I (back to previous page)
A planned program of individual study under the supervision of a member of the faculty.

CH 696 Independent Study II (back to previous page)
A continuation of Independent Study I.

CH 698 Thesis I (back to previous page)
Prerequisite: completion of 15 credits of graduate work. Periodic meetings and discussion of the individual student's progress in the preparation of a thesis.

CH 699 Thesis II (back to previous page)
A continuation of Thesis I.