Parameters for image-map-2:{}
University of New Haven logo
Menacherry, Stanley (full)
Stanley
Menacherry
Ph.D.
Practitioner in Residence
Tagliatela College of Engineering
Chemistry & Chemical Engineering
203-479-4177
BCKM320
Buckman Hall
Biography

    Dr. Menacherry started teaching at the University of New Haven in August 2011 as adjunct in Chemistry. Since January 2013, he has been serving as a Professional In Residence at the university. Dr Menacherry is an entrepreneur, having co-founded two companies: Northeast Bioanalytical laboratories, Hamden, CT which is engaged in quantitation of drugs and metabolites from specimens obtained from clinical trials, and Computer Hospital Inc.,West Haven, CT which is engaged in developing mobile computing for clinical trials and patient enrollment. Prior to starting his own business, Dr Menacherry was employed by major pharma: Abbott Laboratories, IL and Bayer Pharmaceuticals, CT. He was a group leader in the pharmacokinetics and drug metabolism departments of these companies.

    Dr. Menacherry’s research interests are in the field of pharmaceutical chemistry, toxicology, and applications of LC tandem mass spectrometry. His current projects include detection of drugs and metabolites in blood and tissue and the development of databases for tracking laboratory data. 

Academic Credentials

    Education 

    2000- MBA University of New Haven New Haven, CT.

    1995- Certificate in Pharmacokinetics. University of Arizona (Tucson)

    1991- Ph.D. Analytical Chemistry, Emory University, Atlanta, GA.

    1985- MS (Population Sciences), Bombay University (India)

    1979- Diploma in Statistical Quality Control (Indian Statistical Inst.) 

    1977- BS. Chemistry, Biology, Bangalore University, India

    Publications

    1. Safety, Bioavailability, And Pharmacokinetics of VGX-1027-A Novel Oral Anti-Inflammatory Drug In Healthy Human Subjects: Safety, Bioavailability, And Pharmacokinetics of VGX-1027, Lee JC, Menacherry S, Diehl MC, Giffear MD, White CJ, Juba R, Bagarazzi ML, Muthumani K, Boyer J, Agarwal V, Nicoletti F, Bart S, Kim JJ, Weiner DB, and Sardesai NY.  Clinical Pharmacology in Drug Development 04/2015; DOI: 10.1002/cpdd.193

    2. LCMS Method for the Determination of Illicit Drug Residues on Paper Currency. Ieong LC, Menacherry S, Smith FP.  International Chemistry Review-KEI Journals No 1 (2015).

    3. Quantitative Tissue Distribution of BAY38-3441 In Rats.  Menacherry, S, Perrino, P, Ward, D. Proc. Amer Assoc Cancer Res 2000, 41: Abst 3434. 13. 

    4. Quantitation Of A New Macrolide In Plasma By High Performance Liquid Chromatography With Tandem Mass Spectrometric Detection: Comparison With Electrochemical Detection. D.J. Daszkowski, V.S. Ong, S. Menacherry, T. El-Shourbagy, S.L. Carroll, K.C. Marsh, Journal of Liquid Chromatography & Related Technologies, 1999; 22(5):641-657.

    5. Quantitation of TNP-470 And Its Metabolites In Human Plasma: Sample Handling, Assay Performance And Stability.  Ong VS; Stamm GE; Menacherry S; Chu S, J Chromatogr B Biomed Sci Appl, 1998, 710 (1-2):173-82.

    6. A Sensitive and Specific Method for Assay of Sertindole and Its Metabolites in Human, Rat, Dog, and Mouse Plasma Using HPLC with Tandem Mass Spectrometric Detection.  Journal of Liquid Chromatography & Related Technologies, 1997; 20 (14): 2241-2257.

    7. Analytical Method Development for the Simultaneous Quantitation of Dexmedetomidine and Three Potential Metabolites in Plasma. Hui YH, Marsh KC, Menacherry S. J Chromatogr A. 1997 Feb 21;762(1-2):281-91.

    8. Ex Vivo Inhibition Of Beta-Thromboglobulin Release Following Administration To Man Of ABT-299, A Novel Prodrug Of A Potent Platelet Activating Factor Antagonist.  Albert DH; Magoc TJ; Menacherry SD; Morgan DW; Sun E; Reyes AE; Kleinert HD; Carter GW; Summers JB, Inflamm Res, 1997, 46(7):272-7.

    9. Pharmacokinetics Of Sertindole And Dehydrosertindole In Volunteers With Normal Or Impaired Renal Function. Wong SL; Menacherry S; Mulford D; Schmitz PJ; Locke C; Granneman GR, Eur J Clin Pharmacol, 1997, 52(3):223-7.

    10. Effect of Renal Impairment on the Pharmacokinetics of a New Dopaminergic Selective Anti-Psychotic Compound. S.L. Wong, T. Sebree, S. Menacherry, D. Mulford, P. Linnen, G.R. Granneman Clin. Pharmacol  & Therapeutics, 1996,  59(2), 186.

    11. Liquid Chromatography Combined with Tandem Mass Spectrometry for the Confirmation of Sarafloxacin in Catfish Tissue. Schilling J.B. , Cepa S.P., Menacherry, S.D.. Bavda L.T., Heard B.M. and Stockwell B.L. Anal. Chem. 1996, 68 (11), 1905-1909.

    12. Analytical Method Development for the Simultaneous Quantitation of Dexmedetomidine and Three Potential Metabolites in Plasma Using GC/MS with Negative and Positive Ionization. Hui Y.H., Marsh, K.C. and Menacherry S.D.  J. of Chromatography   1997, (A) 762, 281-291.

    13. A Sensitive And Specific Method For The Assay Of Sertindole And It’s Metabolites In Human Serum Using HPLC With Tandem Mass Spectrometric Detection.  Menacherry, S.D., Stamm, G.E. and Chu S.Y.,  J. Liq. Chrom. & Rel. Technol., 1997, 20 (14), 2241-2257.

    14. In Vivo Calibration of Microdialysis Probes for  Exogenous Compounds.  Menacherry S., Hubert W. and Justice J. B. Jr.,  Anal. Chem. 1992, 64 (6), 577-583.

    15. Anomalous Effect of Mazindol on Dopamine Uptake as Measured by In Vivo Voltammetry and Microdialysis.  Ng J., Menacherry S. and Justice J. B. Jr.,  NeuroSci. Letters, 1992, 134 (2), p229-32.

    16. Analysis of 2DG Autoradiograms using Image-Averaging and Image Differencing Procedures For Systems-Level Description of Neurobehavioral Function Hall W.G., Swithers S.E., Agrawal C.M., Burka N.R., Horner J. and Menacherry S.,  Physiol Behav.  1991 50 (1), 109-119.

    17. In Vivo Microdialysis with Thermospray Tandem Mass Spectrometry of the Dopamine Uptake Blocker GBR-12909.   Menacherry S. D. and Justice J. B. Jr.  Anal. Chem.  1990, 26, 587-601.

    18. Differences in the Pharmacokinetics of Cocaine in Naive and Cocaine Experienced Rats. Pan H.T., Menacherry, S. D. and Justice J.B. Jr.,  J. Neurochem. 1990, 56: (4), 1299-1306.

    19. An Orthogonal Array Experimental Design for Determining Important Factors Influencing the Quality of Activated Carbon during the Manufacturing Process. Menacherry S. Rao S. N., Annals of the Indian Statistical Institute, 1979.

    Presentations

    1. Tissue Distribution of 14C [BAY 38-3441], A Glycoconjugate of Camptothecin In Rats. Poster-American Cancer Society (2000).

    2. Pharmacokinetics BAY 38-3441, A Glycoconjugate Of Camptothecin In Dogs.  Poster-American Cancer Society (2000).

    3. “Quantitative LC/MS in a GLP Environment”, Invited speaker-Southeast Regional Conference of the American Association of Pharmaceutical Scientists. Jun 1995, RTP, NC.

    4. Ionspray MS-MS for determination of Abbott-72517 (renin inhibitor) concentration in human plasma. Menacherry, S.D., Matassa, L.C., Chu, M. and Kleinert, H. Presented at the 41st ASMS conference, San Francisco, CA; June, 1993; Abstract Number THP2.

    5. In vivo microdialysis and LC/MS/MS as a powerful new approach for studying the pharmacokinetics and pharmacodynamics of neuroactive drugs in the rat brain.  First International Symposium on Microdialysis and Allied Techniques, Indianapolis, Indiana, May 17, 1989.

    6. Insights from finite element analysis of microdialysis in vivo and in vitro probe dynamics. Federation of American Societies for Experimental Biology, 75th Annual meeting, 1991, Atlanta, GA (Abstract #6935).

    7. Correlation of multiple infusion pharmacokinetics with self administration behavior in rats, Society for Neuroscience, 20th annual meeting, 1990, St. Louis, Mo, (Abstract #310.10, vol 16, p749).

    Courses Taught

            CH 115/116 -  General Chemistry I and II

            CH 117/118 -  General Chemistry I and II Laboratory

            CH 103        -  Introduction to Chemistry