Pauline Schwartz

Education

Ph.D. in Medicinal Chemistry, University of Michigan, 1975
M.S. in Medicinal Chemistry, University of Michigan, 1971
B.S. in Chemistry, Drexel University, 1970. (Magna cum laude)

Publications

Schwartz, P.M., Lepore, Dante, and Barratt, Carl, Computational Models of the Prebiotic Replication of dsRNA under Thermal Cycling Conditions, (in preparation)

Schwartz, P.M., Lepore, D.M., Morneau, B.N., and Barratt, C., Demonstrating optical activity using an iPad, J. Chem. Edu (accepted)

Lepore, Dante, Barratt, Carl, and Schwartz, P.M., Computational models of chemical systems inspired by Braess’ paradox, J. Mathematical Chemistry, 49: 356-370, 2011 (Braess Paradox )

Barratt, Carl, Lepore, Dante M, Cherubini, Matthew, J and Schwartz, P.M., Computational Models of Thermal Cycling in Chemical Systems, International Journal of Chemistry, Vol.2: No.2:, 19-27, 2010

Osipovitch, Daniel C, Gordon, Thomas, Barratt, Carl, and Schwartz, P.M., Chemical and Biomedical Models of Parrando’s Paradox, FASEB, 23: 514.1, 2009 (abstract)

Daniel C., Osipovitch, Barratt, C. and Schwartz, P. M. Systems Chemistry and Parrondo’s Paradox: Computational Models of Thermal Cycling, New Journal of Chemistry 33: 2022-2027, 2009

Menon, G.K., Brandsma, J.L. and Schwartz, P.M. Particle mediated delivery and human skin: Ultrastructural observations on stratum corneum barrier structures. Journal of Skin Pharmacology and Physiology, 20:141-147, 2007.

Milstone, L.M., Asgari, M.M., Schwartz, P.M. and Hardin-Young, J. Growth factor expression, healing and structural characteristics of Grafskin (Apligraf®). Wounds, 12: 12-19, 2000.

Asgari, M.M., Haggerty, J.G., McNiff, J.M., Milstone, L.M. and Schwartz, P.M.; Expression and localization of thymidine phosphorylase/platelet-derived endothelial cell growth factor in skin and epidermal tumors. J Cut. Pathol. 26: 287-294, 1999.

Schwartz, P.M., Haggerty, J.G. and Cheng, Y-C. β-L-1,3-Dioxolane-cytidine: A novel nucleoside that inhibits proliferation and induces differentiation of keratinocytes in vitro. Skin Pharmacol, 11: 207-213, 1998.

Fenjves, E.S., Schwartz, P.M. Blaese, R.M., and Taichman, L.B. Keratinocyte gene therapy for adenosine deaminase deficiency: A model approach for inherited metabolic disorders. Human Gene Therapy, 8: 911-917, 1997.

Schwartz, P.M., Barnett, S.K. and Milstone, L.M. Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis. J. Dermatologic Sci. 9: 129, 1995.

Schwartz, P.M., Barnett, S.K., Atillasoy, E.J. and Milstone, L.M. Methotrexate induces
differentiation of human keratinocytes. Proc. Natl. Acad. Sci., USA, 89:594, 1992

Schwartz, P.M., Barnett, S.K. and Reuveni, H. Thymidine salvage changes with differentiation in human keratinocytes in vitro. J. Invest. Dermatol., 97: 1057, 1991.

Doctoral Dissertation:

9-β-D-Arabinofuranosyladenine: Metabolism and Effects of Virus Replication and DNA
Synthesis in Uninfected and Herpes Simplex Virus-Infected KB Cells. Doctorate in Medicinal
Chemistry. The University of Michigan, 1975

Provisional Patent:

Schwartz, P.M. and Barratt, C.  Wagering game using a series of random binary events and having a selectable house advantages, , Filed March 2009.

Courses Taught

Undergraduate:

CH501 Advanced Organic Chemistry
CH412 Seminar
CH351 * Qualitative Organic Chemistry
CH341 Synthetic Methods in Chemistry
CH201-CH204 Organic Chemistry I and II and Laboratories
CH115-CH118 General Chemistry I and II and Laboratories
CH107, CH108 * Introduction to Organic Chemistry and Laboratory
CH105 Introduction to General and Organic Chemistry with Laboratory
CH103 , CH104 Introduction to General Chemistry and Laboratory
EAS 120 General Chemistry with Applications to Biosystems
* no longer offered

Honors Courses:

-Emerging Infectous Diseases: History; Science and Medicine (with Charles Vigue)
-Origins of the Universe and Life: Views of Science and Religion (with Martin O'Connor)

Graduate:
CH650 Medicinal Chemistry
CH655 Pharmacology

Other

Current University Committees:

• Member and Chair, University Information Technology Advisory Committee - 2003-2010
• Member, University Institutional Review Board - 2003-Current
• Leader, NEASC Team (Library and Information Services) - 2009-2010
• Team leader for UNH Experiential Education Initiative in Undergraduate Research and Scholarship

Recent Professional Activities and Awards:

• University Research Scholar – 2007-2012
• Visiting Associate Professor of Dermatology at Yale University - 2003 - present
• UNH Award for Excellence in Teaching – May, 2009
• UNH Center for Experiential Education 2009 LEARN Award for Excellence for Faculty Mentored Undergraduate Research
• Graduate Experiential Education Academy - 2008
• Member and President, UNH Society for Experiential Education - 2009
• UNH Summer Fellowship and Research Awards (2005-2010)