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Dr. Sapi's Lab/Lyme Disease Group

Recent publications from our group:

  • Sapi, E. and MacDonald A. Biofilms of Borrelia burgdoferi in chronic cutaneous borreliosis. Am J Clin Pathol 129. p.988-989, 2008.
  • Sapi, E., Hessberger, M., Bober, J., Montagna, M., Raman, M., Reddy, M., and Melillo A. Pathogenic Co-infections in Ixodes scapularis Ticks in Southern Connecticut. Peer Observations,  February-March issue 17-21, 2009.
  • Datar, A., Kaur, N., Patel, S., Luecke D.F., and Sapi E. In vitro effectiveness of Samento and Banderol herbal extracts on the different morphological forms of  Borrelia burgdorferi. Townsend Letter, July, 324, 87- 90, 2010.
  • Sapi E, Kaur N, Anyanwu S, Luecke DF, Datar, A, Patel S,  Rossi MJ, and Stricker RB. Evaluation of in vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi. Infection and Drug Resistance, 2011, 4(1) 97-113, 2011. Link: http://www.dovepress.com/articles.php?article_id=7341
  • Middelveen MJ, Divya Burugu D, Akhila Poruri A, Jennie Burke J, Peter J Mayne PJ, Sapi E, Douglas G Kahn DG, Stricker RB. Association of spirochetal infection with Morgellons disease. [v1; ref status: indexed, http://f1000r.es/8g] F1000Research 2013, 2:25 (doi: 10.3410/f1000research.2-25.v1).

 

Recent projects:

2014-present     M.S. Thesis Katherine R Filush B.S. “Investigation of Borrelia biofilm development in a mouse model”. University of New Haven, Department of Biology and Environmental Science.

2014-present     M.S. Thesis  Shafiq Shaikh B.S. “Investigation of Borrelia biofilm development by AFM”. University of New Haven, Department of Biology and Environmental Science.

2014-present     M.S. Thesis  Kayla Sokaras B.S. “Borrelia biofilm and amyloids”. University of New Haven, Department of Biology and Environmental Science.

2014-present     M.S. Thesis  Jasmin Maghsoudlou B.S. “Borrelia amyloids in MS”. University of New Haven, Department of Biology and Environmental Science.

2013-present     M.S. Thesis Priyankannabel Theophilus B.S. “Biofilm induction signaling pathways in Borrelia burgdorferi”. University of New Haven, Department of Biology and Environmental Science.

2013-present     Undergraduate Research, Dylan J Haenel “Effect of allicin in the different morphological form of Borrelia” University of New Haven, Department of Biology and Environmental Science.

2013-present     Undergraduate Research, Christina Kling “Effect of Blue Scorpio venom on the different morphological forms of Borrelia” University of New Haven, Department of Biology and Environmental Science

2013-present     M.S. Thesis Kunthavai Balasubramanian B.S. “Identification of Borrelia burgdorferi in Infected Human Skin and Tick Gut Tissues”. University of New Haven, Department of Biology and Environmental Science.

2013-present     M.S. Thesis , Cheryl Bandoski B.S. “Identification of Borrelia burgdorferi in Morgellon Tissues”. University of New Haven, Department of Biology and Environmental Science.

2013-present     M.S. Thesis  Maria Jacintha Victoria B.S. “Effect of Proteolitic Enzymes on Borrelia Biofilm”. University of New Haven, Department of Biology and Environmental Science.

2013-2013          Undergraduate Research, Eric Christie B.S. “Development of Novel 16S rDNA Beacon DNA Probes for the Detection of Borrelia” University of New Haven, Department of Biology and Environmental Science.

2013-2013          Undergraduate Research, Brittany L Jones “Development of Novel Flagella Beacon DNA Probes for the Detection of Borrelia” University of New Haven, Department of Biology and Environmental Science.

2012-2013          M.S. Thesis  Viet Truc Pham B.S. “Identification of Borrelia burgdorferi biofilm in Erythema Chronicum Migrans”. University of New Haven, Department of Biology and Environmental

2012-2013          M.S. Thesis  Divya Burugu B.S. “Decorin role in Borrelia burgdorferi attachment”. University of New Haven, Department of Biology and Environmental Science.

2011-2013          M.S. Thesis Akhila Poruri B.S. “Matrix requirement for Borrelia burgdorferi attachment”. University of New Haven, Department of Biology and Environmental Science.

2011-2013          M.S. Thesis  Tinatin Tsitlavishvili MD “Detection of Borrelia burgdorferi using nanosensor technology”. University of New Haven, Department of Biology and Environmental Science.

2011-2012          M.S. Research  Phillips Daniel B.S. “Cumultive effect of EDTA and proteolytic enzymes on the formation of Borrelia burgdorferi biofilm”. University of New Haven, Department of Biology and Environmental Science.

2010-present     M.S. Thesis , David F Luecke B.S. “Characterization of the EPS components of Borrelia burgdorferi’s biofilm”. University of New Haven, Department of Biology and Environmental Science.

2010-2011          M.S. Thesis  Yram Foli B.S. “In vitro effectiveness of medicinal aromatic oils on the different forms of Borrelia burgdorferi”. University of New Haven, Department of Biology and Environmental Science.

2010- 2011         Undergraduate HONOR Research Thesis  Lindsley Gress.“Enzymatic sensitivity of the biofilm form of Borrelia burgdorferi”  University of New Haven, Department of Biology and Environmental Science.

2010- 2011         Undergraduate HONOR Research Thesis  Gabriela Sacchi “Potential presence of XMRV retrovirus in Ixodes scapularis ticks” University of New Haven, Department of Biology and Environmental Science.

2010- 2011         Undergraduate Research  Gloria Frankson, “Effect of allicin on the different formations of Borrelia burgdorferi” SURF presentation 2010 September, University of New Haven, Department of Biology and Environmental Science.

2010- 2011         M.S.  Research Project  Shanmugapriya Selvaraj B.S. “Macrolide sensitivity of different forms of Borrelia burgdorferi”. University of New Haven, Department of Biology and Environmental Science.

2010- 2011         M.S. Research Project  Michael Faulkner B.S. “Identification of genetic markers for Borrelia burgdorferi biofilm”. University of New Haven, Department of Biology and Environmental Science.

2010- 2011         M.S. Research Project  Dellora Daniel B.S. “Effect of marine alkaloids on Borrelia burgdorferi biofilm”. University of New Haven, Department of Biology and Environmental Science.